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The University of South Carolina Department of Electrical Engineering Presents Photoacoustic tomography and its applications to animal brain imaging Dr. Xinmai Yang When: 1:30PM on Monday, February 25, 2008 Where: 3D05 in Swearingen Center Abstract Photoacoustic tomography (PAT) is a novel, hybrid, and nonionizing imaging modality that combines the merits of both optical and ultrasonic imaging methods. It is highly sensitive to the optical absorption of biological tissue. PAT provides greater spatial resolution than purely optical imaging in deep regions while simultaneously overcoming the disadvantages of ultrasonic imaging regarding both biochemical contrast and speckle artifact. PAT can provide high spatial resolution images with optical contrast in a region up to 5.2 cm deep in biological tissue, whereas purely optical imaging techniques cannot provide high spatial resolution in regions beyond the quasiballistic regime (1 mm deep) because of the strong scattering in biological tissues. PAT has been successfully applied to the visualization of different structures in biological tissues and especially useful in imaging the cerebral cortex of small animals. In this talk, I will summarize the application of PAT on small animal imaging, including structural imaging, functional imaging, and molecular imaging. I will also present the results of PAT of monkey brain cortex, and demonstrate that PAT of the brain cortex is capable of surviving the ultrasound signal attenuation and distortion caused by a relatively thick skull. Everyone is welcome to attend. All Mechanical Engineering graduate students are required to attend the seminar. Light refreshments will be served.
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